Are Biosearch dyes compatible with DNA sequencing or fragment analyzers?

Biosearch dyes have not been tested for compatibility in these instruments. While the potential is there, dye substitution is made more complicated by the fact that many DNA sequencers are calibrated with FRET constructs composed of two dyes such as FAM/NED, though the construct is named only for one dye in the pair. In this example the calibrant would be named, NED.

Biosearch dyes are principally intended for use in probe hybridization studies such as qPCR and SNP genotyping. Using appropriate calibration methods, Biosearch dyes can be used with most real-time PCR machines.

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